TLC Laser Eye Center of St. Louis is located in West St. Louis County between Interstate 64/Highway 40 and Olive Boulevard on North New Ballas Road.

The building is located on the west side of N. New Ballas Road and is accessible from either I-270 or I-64.

From I-270: Exit Ladue Road and go East. Turn left on N. New Ballas Road and turn left to the Ballas Place building.

From I-64/Highway 40: Exit Ballas Road and go North. Turn left to the Ballas Place building.